Parameter
| Biomarker | miRNA-21 | Full name | microRNA-21 | Molecular Type | microrna |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, prognosis, and treatment resistance | ||
| Disease | Colorectal Cancer (CRC) | Disease Subtypes | / | ||
| Organ | Colorectal | Test Sample / Technology Platform | Tumor tissue/blood/stool (qRT-PCR, RNA sequencing) | ||
| Pathobiological Mechanisms | Targeting tumor suppressor genes such as PTEN and TP53INP1 can promote cell proliferation, inhibit apoptosis, and enhance the invasion and metastasis of CRC cells | ||||
| Clinical Availability Status | Clinical research phase: a large number of clinical studies confirmed that its high expression associated with poor prognosis of CRC, in the stage of clinical transformation | ||||
| Notes and Dynamics | It is one of the most widely studied miRNA markers in CRC. Its detection methods are mature and it is expected to enter clinical application quickly | ||||