Parameter
| Biomarker | CXCL14 | Full name | Chemokine (C-X-C motif) ligand 14 (Breast and kidney-expressed chemokine) | Molecular Type | Chemokines |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis and Prognosis | ||
| Disease | Colorectal Cancer (CRC) | Disease Subtypes | / | ||
| Organ | Colorectal | Test Sample / Technology Platform | Tumor tissue/feces (qRT-PCR, methylation-specific PCR) | ||
| Pathobiological Mechanisms | It plays a tumor suppressor role by regulating immune cell infiltration, and its promoter methylation leads to down-regulation of expression and promotes CRC progression | ||||
| Clinical Availability Status | Study validation: Stool test shows diagnostic potential and is in preclinical research stage | ||||
| Notes and Dynamics | The expression level decreases with the progression of CRC and can be used as a marker for good prognosis. Restoring its expression can inhibit CRC proliferation and metastasis | ||||