Parameter
| Biomarker | Circulating Tumor DNA (ctDNA) | Full name | Circulating Tumor DNA | Molecular Type | Circulating nucleic acids |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, monitoring, and treatment prediction | ||
| Disease | Colorectal Cancer (CRC) | Disease Subtypes | / | ||
| Organ | Colorectal | Test Sample / Technology Platform | Blood (NGS, digital PCR) | ||
| Pathobiological Mechanisms | Free DNA in tumor cells released into the blood, carry mutations in tumor specificity (such as sets, mutated BRAF), can reflect the tumor burden and response to treatment | ||||
| Clinical Availability Status | Clinically available (monitoring) : It has been used for postoperative recurrence monitoring and treatment response assessment of CRC, and some centers are included in routine clinical practice | ||||
| Notes and Dynamics | Is an ideal marker, real-time dynamic monitor progress CRC liquid biopsy technology mature and make its application scenario development | ||||