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1040

Parameter
Biomarker CEL Full name Carboxyl ester lipase Molecular Type protein
Molecular Formula Molecular Weight Core Functional Dimensions Risk prediction, metabolic regulation
Disease Esophageal Carcinoma Disease Subtypes /
Organ Esophagus Test Sample / Technology Platform Tissue/plasma (MR Analysis, IHC)
Pathobiological Mechanisms It participates in lipid metabolism and affects tumor microenvironment and inflammatory response by regulating fatty acid metabolism. High expression associated with poor prognosis of ESCC, taurocholic acid can activate its function
Clinical Availability Status Clinical research phase: has clear its causal relationship with ESCC, related mechanism of activator is preliminary already clarify
Notes and Dynamics Is closely related to the metabolism of bile acid, provide theory basis for metabolic reprogramming related target therapy

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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