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1041

Parameter
Biomarker KLK13 Full name Kallikrein-related peptidase 13 Molecular Type Proteins
Molecular Formula Molecular Weight Core Functional Dimensions Prognosis and disease progression monitoring
Disease Esophageal Carcinoma Disease Subtypes /
Organ Esophagus Test Sample / Technology Platform Tissue (IHC, qPCR)
Pathobiological Mechanisms It belongs to the serine protease family and participates in the proteolytic process of tumorigenesis. Its high expression is related to the tumor progression, advanced stage and poor prognosis of ESCC, and its expression change can predict disease progression
Clinical Availability Status Clinical study phase: multiple clinical cohorts were used to verify its correlation with ESCC prognosis
Notes and Dynamics It can be used as a unique molecule to monitor the progression of ESCC, and its regulatory mechanism and targeting strategy deserve further exploration

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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