Parameter
| Biomarker | GNRH2 | Full name | Gonadotropin-releasing hormone 2 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Risk prediction, cancer suppression | ||
| Disease | Esophageal Carcinoma | Disease Subtypes | / | ||
| Organ | Esophagus | Test Sample / Technology Platform | Tissue/plasma (MR Analysis, qPCR) | ||
| Pathobiological Mechanisms | It is widely distributed in the central nervous system and peripheral tissues and plays a tumor suppressor role by inhibiting tumor cell proliferation, migration and ribosomal phosphorylation protein expression. SNP rs6051545 has a negative regulatory effect on ESCC | ||||
| Clinical Availability Status | Clinical research stage: Mendelian randomization analysis confirmed its causal relationship with ESCC, and no direct targeted drugs were available | ||||
| Notes and Dynamics | In a wide variety of tumor has antiproliferative and its effect on promoting apoptosis, provide a new potential target for ESCC targeted treatment | ||||