Parameter
| Biomarker | Fusobacterium nucleatum | Full name | Fusobacterium nucleatum | Molecular Type | Microbes |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Prognosis, immune regulation | ||
| Disease | Esophageal Carcinoma | Disease Subtypes | / | ||
| Organ | Esophagus | Test Sample / Technology Platform | Esophageal tissue/stool (16S rRNA sequencing, qPCR, IHC) | ||
| Pathobiological Mechanisms | By activating NOD1 RIPK2 / the nf-kappa B pathway, promote chemokine activation mechanism, enhance tumor invasive; It is related to the clinical stage progression, poor prognosis and immunotherapy resistance of ESCC | ||||
| Clinical Availability Status | Clinical research phase: various clinical studies verify the value of his as a prognostic marker | ||||
| Notes and Dynamics | It is a key pathogenic microorganism in the tumor microenvironment of ESCC and can be used as a potential target for non-invasive diagnosis and prognostic evaluation | ||||