Parameter
| Biomarker | Porphyromonas gingivalis | Full name | Porphyromonas gingivalis | Molecular Type | Microbes |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Prognosis, immune regulation | ||
| Disease | Esophageal Carcinoma | Disease Subtypes | / | ||
| Organ | Esophagus | Test Sample / Technology Platform | Esophageal tissues (16S rRNA sequencing, qPCR, IHC) | ||
| Pathobiological Mechanisms | Activation of PI3K/Akt pathway can inhibit epithelial cell apoptosis, induce IL-6 expression to promote epithelial-mesenchymal transition and myeloid-derived suppressor cell recruitment, and enhance TGF-β/Smad signaling to promote tumor growth and metastasis | ||||
| Clinical Availability Status | Clinical research stage: it is closely related to the advanced clinical stage and poor prognosis of ESCC | ||||
| Notes and Dynamics | Its abundance changes can monitor progress ESCC, provide the basis for targeted treatment strategy of microbiota | ||||