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1045

Parameter
Biomarker Streptococcus Full name Streptococcus spp. Molecular Type Microbes
Molecular Formula Molecular Weight Core Functional Dimensions Diagnosis, Prognosis
Disease Esophageal Carcinoma Disease Subtypes /
Organ Esophagus Test Sample / Technology Platform Esophageal tissue/stool (16S rRNA sequencing, qPCR)
Pathobiological Mechanisms Abnormal abundance is related to the occurrence of ESCC, and the high expression of some subtypes is related to the poor prognosis of patients, which is involved in the regulation of inflammatory response in tumor microenvironment
Clinical Availability Status Clinical phase: As a key marker in the gut and esophageal microbiota, it has been validated in multiple cohorts
Notes and Dynamics It can be used as an auxiliary marker for non-invasive diagnosis, and its synergistic effect with other microorganisms deserves further study

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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