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1047

Parameter
Biomarker Faecalibacterium Full name Faecalibacterium prausnitzii Molecular Type Microbes
Molecular Formula Molecular Weight Core Functional Dimensions Diagnosis, Prognosis
Disease Esophageal Carcinoma Disease Subtypes /
Organ Esophagus Test Sample / Technology Platform Stool (16S rRNA sequencing)
Pathobiological Mechanisms As a short chain fatty acid bacteria, abundance lower will destroy the integrity of intestinal barrier, enhance intestinal permeability and inflammation, indirectly promote the development of ESCC occurs
Clinical Availability Status Clinical research phase: Its diagnostic and prognostic relevance has been validated in multiple ESCC cohorts
Notes and Dynamics The changes in their abundance can reflect the imbalance of intestinal microecology and provide ideas for the treatment of combined microecological agents

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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