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1048

Parameter
Biomarker Prevotella Full name Prevotella spp. Molecular Type Microbes
Molecular Formula Molecular Weight Core Functional Dimensions Diagnosis, prognosis, immunomodulation
Disease Esophageal Carcinoma Disease Subtypes /
Organ Esophagus Test Sample / Technology Platform Esophageal tissue/stool (16S rRNA sequencing, qPCR)
Pathobiological Mechanisms Some subtype abundance anomalies associated with ESCC progress, by adjusting the indoles metabolites such as tumor microenvironment, to participate in the process of immunosuppression
Clinical Availability Status Clinical research stage: It has been frequently identified in ESCC microbiota studies with good diagnostic specificity
Notes and Dynamics The dual role of ESCC microbiota (cancer-promoting and cancer-suppressing in some subtypes) needs to be further clarified to provide a basis for precise targeting of microbiota

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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