Parameter
| Biomarker | Atopobium | Full name | Atopobium spp. | Molecular Type | Microbes |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis and monitoring of disease progression | ||
| Disease | Esophageal Carcinoma | Disease Subtypes | / | ||
| Organ | Esophagus | Test Sample / Technology Platform | Esophageal tissues (16S rRNA sequencing) | ||
| Pathobiological Mechanisms | In GERD-BE-EAC, its abundance gradually increases during the progression of GERD-BE-EAC, which is involved in the regulation of lipopolysaccharide biosynthesis and inflammatory response and promotes malignant transformation | ||||
| Clinical Availability Status | Clinical research stage: it can BE used as a potential marker to monitor the progression of BE to EAC | ||||
| Notes and Dynamics | It is a key microbial marker in the occurrence and development of EAC and provides targets for early intervention | ||||