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1053

Parameter
Biomarker IGLV7-43 Full name Immunoglobulin lambda variable 7-43 Molecular Type Nucleic acid (immunoglobulin gene)
Molecular Formula Molecular Weight Core Functional Dimensions Prognosis
Disease Esophageal Carcinoma Disease Subtypes /
Organ Esophagus Test Sample / Technology Platform Tissues (qPCR, sequencing)
Pathobiological Mechanisms It belongs to λ type immunoglobulin light chain. Its low expression is related to the poor prognosis of ESCC patients and participates in the regulation of tumor-specific immune response
Clinical Availability Status Clinical research stage: As an important part of the prognostic model, its immune regulatory mechanism needs to be further elucidated
Notes and Dynamics It provides new molecular markers for immune-related prognosis evaluation of ESCC and is expected to optimize the existing prognostic prediction system

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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