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1055

Parameter
Biomarker HSP90B1 Full name Heat shock protein 90 beta family member 1 Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Risk prediction, protein folding regulation
Disease Esophageal Carcinoma Disease Subtypes /
Organ Esophagus Test Sample / Technology Platform Tissue/plasma (MR Analysis, IHC)
Pathobiological Mechanisms It is involved in protein folding and stability, high expression increases the risk of ESCC, and promotes disease progression by regulating tumor cell stress response and survival
Clinical Availability Status Clinical research phase: the causal relationship has been verified by MR Analysis, and related targeted inhibitors are being explored
Notes and Dynamics This study provides new ideas for the targeted molecular chaperone therapy of ESCC, which has certain clinical transformation potential

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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