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1056

Parameter
Biomarker PLA2R1 Full name Phospholipase A2 receptor 1 Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Risk prediction, immune regulation
Disease Esophageal Carcinoma Disease Subtypes /
Organ Esophagus Test Sample / Technology Platform Tissue/plasma (MR Analysis, qPCR)
Pathobiological Mechanisms It is involved in the regulation of phospholipid metabolism and immune response, and its high expression increases the risk of ESCC and affects disease progression by regulating the inflammatory response of tumor microenvironment
Clinical Availability Status Clinical research stage: Mendelian randomization analysis confirmed the causal relationship between the tumor and ESCC, and the immune regulation mechanism needs further study
Notes and Dynamics It is a potential risk marker related to ESCC metabolism, which provides a new direction for multi-target combined therapy

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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