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1057

Parameter
Biomarker CTSF Full name Cathepsin F Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Risk prediction, protease regulation
Disease Esophageal Carcinoma Disease Subtypes /
Organ Esophagus Test Sample / Technology Platform Tissue/plasma (MR Analysis, Western blotting)
Pathobiological Mechanisms It is a cysteine protease, and its high expression increases the risk of ESCC. It participates in multiple processes of tumor occurrence and development through proteolysis
Clinical Availability Status Clinical research stage: the causal relationship has been verified by MR Analysis, and the functional mechanism research is in the basic stage
Notes and Dynamics To provide a new target for ESCC protease targeted therapy, its clinical application value needs to be further verified

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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