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1058

Parameter
Biomarker VIT Full name Vitamin D-binding protein (GC protein) / Vitamin transporter protein Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Risk prediction, metabolic regulation
Disease Esophageal Carcinoma Disease Subtypes /
Organ Esophagus Test Sample / Technology Platform Tissue/plasma (MR Analysis, IHC)
Pathobiological Mechanisms It is involved in the regulation of vitamin metabolism and cell function, and its high expression increases the risk of ESCC and promotes disease progression by regulating metabolic reprogramming of tumor cells
Clinical Availability Status Clinical research stage: Mendelian randomization analysis confirms the causal relationship between ESCC and metabolic regulation mechanism needs to be clarified
Notes and Dynamics It is a potential metabolism-related marker of ESCC, which provides ideas for metabolic intervention combined with cancer therapy

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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