Parameter
| Biomarker | Ki-67 (proliferation index) | Full name | Antigen Ki-67 | Molecular Type | Proteins |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Prognosis, Prediction | ||
| Disease | Gastric Cancer | Disease Subtypes | / | ||
| Organ | Stomach | Test Sample / Technology Platform | Tumor tissue (IHC) | ||
| Pathobiological Mechanisms | Cell proliferation-associated antigens are expressed in G1, S, G2 and M phases of the cell cycle. The Ki-67 index of gastric cancer tissue reflects the proliferation activity of tumor cells. Patients with high Ki-67 index (>50%) have strong tumor invasion and good response to chemotherapy, but tend to relapse | ||||
| Clinical Availability Status | Clinically usable (prognostic evaluation) : Routine pathological reports contain indicators for predicting the prognosis of gastric cancer and predicting the response to chemotherapy | ||||
| Notes and Dynamics | Ki-67 index, the basic indicator of pathological evaluation of gastric cancer, is positively correlated with tumor grade and stage. Combined with p53 and HER2 detection, the prognosis of gastric cancer can be more accurately judged | ||||