Parameter
| Biomarker | Tu M2-PK | Full name | Tumor M2 pyruvate kinase | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis (advanced stage) | ||
| Disease | Pancreatic Cancer | Disease Subtypes | / | ||
| Organ | Pancreas | Test Sample / Technology Platform | Serum (Enzyme activity measurement) | ||
| Pathobiological Mechanisms | Tumor pyruvate kinase isoenzyme, as a key rate-limiting enzyme of glycolysis, is abnormally expressed in tumor cells and promotes tumor metabolic reprogramming | ||||
| Clinical Availability Status | Clinical research phase: it is significantly elevated in patients with advanced PDAC and chronic pancreatitis, and its early diagnostic value is limited | ||||
| Notes and Dynamics | It has a certain reference value for the diagnosis of advanced PDAC, but it cannot distinguish early tumors from benign lesions, so it needs to be combined with imaging examination | ||||