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1105

Parameter
Biomarker CEACAM1 Full name Carcinoembryonic antigen-related cell adhesion molecule 1 Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Diagnosis, differential diagnosis
Disease Pancreatic Cancer Disease Subtypes /
Organ Pancreas Test Sample / Technology Platform Serum, tissues (immunohistochemistry, mass spectrometry)
Pathobiological Mechanisms Belong to the immunoglobulin superfamily, involved in intercellular communication, proliferation and invasion regulation and expression in PDAC, can distinguish between PDAC and healthy people and precancerous lesions
Clinical Availability Status Clinical research phase: diagnostic sensitivity and specificity is better than that of CA19-9, joint CA19-9 can improve accuracy
Notes and Dynamics The expression of CA19-9 in pancreatic intraepithelial neoplasia (PanIN) has been abnormal, which is expected to be used for monitoring and early diagnosis of precancerous lesions

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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