Parameter
| Biomarker | OPN | Full name | Osteopontin | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Differential diagnosis and prognostic evaluation | ||
| Disease | Pancreatic Cancer | Disease Subtypes | / | ||
| Organ | Pancreas | Test Sample / Technology Platform | Serum (Immunoassay) | ||
| Pathobiological Mechanisms | Osteopontin, by regulating cell adhesion, migration, and inflammatory reaction involved in tumor progression, its rise and reduce tumor invasive enhancement, survival | ||||
| Clinical Availability Status | Clinical research phase: it can distinguish PDAC from chronic pancreatitis, and the combination of TIMP-1 and CA19-9 can improve the diagnostic efficiency | ||||
| Notes and Dynamics | When the cut-off value is > 102 ng/ml, it is meaningful to distinguish PDAC from chronic pancreatitis, and high expression indicates poor prognosis | ||||