Parameter
| Biomarker | MIC-1 | Full name | Macrophage inhibitory cytokine-1 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Early diagnosis and postoperative monitoring | ||
| Disease | Pancreatic Cancer | Disease Subtypes | / | ||
| Organ | Pancreas | Test Sample / Technology Platform | Serum (immunoassay) | ||
| Pathobiological Mechanisms | Macrophage inhibitory cytokine-1, which belongs to the TGF-β superfamily, is abnormally secreted in the tumor microenvironment and participates in the regulation of tumor cell proliferation and immunosuppression | ||||
| Clinical Availability Status | In the clinical research phase, it can be elevated in patients with early PDAC, including CA19-9 negative cases | ||||
| Notes and Dynamics | The sensitivity of CA19-9 is better than that of CA19-9, but the specificity is low. The expression of CA19-9 decreases after surgery and increases again when recurrence occurs. It has the potential for early diagnosis and treatment monitoring | ||||