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1110

Parameter
Biomarker PiR - 366845. Full name piRNA-366845 Molecular Type piRNA
Molecular Formula Molecular Weight Core Functional Dimensions Diagnosis differential
Disease Pancreatic Cancer Disease Subtypes /
Organ Pancreas Test Sample / Technology Platform Tissues, Cell lines (Next generation sequencing)
Pathobiological Mechanisms By PIWIL4 regulation, the pancreas in health and normal cell lines high expression, expressed PDAC cells significantly lower, with tumor suppressor related function
Clinical Availability Status Basic research stage: Its expression differences have been verified by NGS, showing diagnostic potential
Notes and Dynamics They are low expression in PDAC cell lines and high expression in normal PDAC tissues, which are potential diagnostic differential markers, but need to be further verified in clinical samples

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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