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Parameter
Biomarker piR-017061 Full name piRNA-017061 Molecular Type piRNA
Molecular Formula Molecular Weight Core Functional Dimensions Tumor suppressor, therapeutic target
Disease Pancreatic Cancer Disease Subtypes /
Organ Pancreas Test Sample / Technology Platform Tissues and cell lines (next-generation sequencing, co-immunoprecipitation)
Pathobiological Mechanisms Belong to the suppressor piRNA, forming complexes with PIWIL1, degradation EFNA5 mRNA, inhibition of pancreatic cancer cell growth, invasion and metastasis
Clinical Availability Status Basic research stage: in vitro and in vivo experiments to verify its tumor suppressive effect and provide ideas for therapeutic targets
Notes and Dynamics Cut in PDAC organization, its control shaft/PIWIL1 EFNA5 piR - 017061 is expected to become a key pathway for the treatment of intervention

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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