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1113

Parameter
Biomarker EPS8 Full name Epidermal growth factor receptor pathway substrate 8 Molecular Type Proteins
Molecular Formula Molecular Weight Core Functional Dimensions Early diagnosis and recurrence monitoring
Disease Pancreatic Cancer Disease Subtypes /
Organ Pancreas Test Sample / Technology Platform Serum (Exosome isolation + Mass spectrometry)
Pathobiological Mechanisms The epidermal growth factor receptor pathway substrate 8, involved in tumor cell migration, invasion, and signal transduction, in PDAC secrete in the body can be detected early
Clinical Availability Status Clinical research phase: It has been validated in patients with early PDAC and is expected to be used for recurrence monitoring
Notes and Dynamics Combination with GPRC5C can improve the accuracy of early diagnosis, and its expression changes are synchronized with tumor progression

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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