Parameter
| Biomarker | hnRNPU | Full name | Heterogeneous nuclear ribonucleoprotein U | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Regulation of tumor progression | ||
| Disease | Pancreatic Cancer | Disease Subtypes | / | ||
| Organ | Pancreas | Test Sample / Technology Platform | Tissues and cell lines (immunoprecipitation, mass spectrometry) | ||
| Pathobiological Mechanisms | As RNA binding protein, combined with piRNA - 1742, regulating the USP8 mRNA stability, suppress MUC12 ubiquitin, promote the development of tumor | ||||
| Clinical Availability Status | Basic research phase: the experiment validate its effect on promoting carcinoma in vivo and in vitro, provide targets for mechanism study | ||||
| Notes and Dynamics | Abnormal expression in PDAC, involved in regulating cell proliferation and tumor, and its related pathways is expected to become targets for intervention | ||||