Parameter
| Biomarker | METTL14 | Full name | Methyltransferase-like 14 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Regulation of tumorigenesis | ||
| Disease | Pancreatic Cancer | Disease Subtypes | / | ||
| Organ | Pancreas | Test Sample / Technology Platform | Organize, cell line (immunohistochemical, mass spectrometry) | ||
| Pathobiological Mechanisms | Participate in m6A RNA methylation process, interact with piRNA - 14633, enhance METTL14 and CYP1B1 is expressed, promotes tumorigenesis | ||||
| Clinical Availability Status | Basic research phase: has clear its role in the tumorigenesis, provide ideas for epigenetic therapy | ||||
| Notes and Dynamics | Abnormal expression in PDAC, affect gene expression, through regulating the RNA methylation is potential targeted therapeutic targets | ||||