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1128

Parameter
Biomarker TFF2 Full name Trefoil factor 2 Molecular Type Proteins
Molecular Formula Molecular Weight Core Functional Dimensions Precancerous lesion surveillance
Disease Pancreatic Cancer Disease Subtypes /
Organ Pancreas Test Sample / Technology Platform Tissue, pancreatic juice (immunoassay, mass spectrometry)
Pathobiological Mechanisms A member of trefoil factor family, it is involved in the maintenance of pancreatic ductal epithelial homeostasis, and its deficiency is associated with the accelerated development of IPMN
Clinical Availability Status Clinical research phase: abnormal expression in IPMN organizations, to evaluate risk of malignant transformation
Notes and Dynamics There are heterogeneous molecular forms of IPMN with tumor suppressive effects, and their expression status can assist in judging the malignant potential of IPMN

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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