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1132

Parameter
Biomarker p-tau (181, 217) Full name Phosphorylated tau (181, 217) Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Diagnosis, Prognosis
Disease Acute pancreatitis (AP) Disease Subtypes /
Organ Pancreas Test Sample / Technology Platform CSF/Plasma (SIMOA, IP-MS)
Pathobiological Mechanisms Tau protein phosphorylation cause nerve fiber entanglement, cytoskeleton damage neurons, the nerve injury induced by abnormal expression and AP
Clinical Availability Status Clinical validation/guideline recommendation: CSF p-tau is the core marker for the diagnosis of related nerve injury; Plasma P-tau 217 has excellent diagnostic performance
Notes and Dynamics P - tau217 specificity is higher than p - tau181 is AP related nerve complications, evaluate the potential of molecular

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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