Parameter
| Biomarker | p-tau (181, 217) | Full name | Phosphorylated tau (181, 217) | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, Prognosis | ||
| Disease | Acute pancreatitis (AP) | Disease Subtypes | / | ||
| Organ | Pancreas | Test Sample / Technology Platform | CSF/Plasma (SIMOA, IP-MS) | ||
| Pathobiological Mechanisms | Tau protein phosphorylation cause nerve fiber entanglement, cytoskeleton damage neurons, the nerve injury induced by abnormal expression and AP | ||||
| Clinical Availability Status | Clinical validation/guideline recommendation: CSF p-tau is the core marker for the diagnosis of related nerve injury; Plasma P-tau 217 has excellent diagnostic performance | ||||
| Notes and Dynamics | P - tau217 specificity is higher than p - tau181 is AP related nerve complications, evaluate the potential of molecular | ||||