Parameter
| Biomarker | Nerve filament light chain (NfL) | Full name | Neurofilament light chain | Molecular Type | protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Monitoring, prognosis | ||
| Disease | Acute pancreatitis (AP) | Disease Subtypes | / | ||
| Organ | Pancreas | Test Sample / Technology Platform | CSF/Plasma (SIMOA) | ||
| Pathobiological Mechanisms | Axon damage after the release of cytoskeleton proteins, is a specific neurons damage marks, the AP caused by systemic inflammation can result in the release | ||||
| Clinical Availability Status | Research/clinical monitoring tools: widely used in clinical trials for effectiveness monitoring indicators; Clinically used to assess the progression of nerve injury | ||||
| Notes and Dynamics | It is elevated in a variety of diseases such as AP, MS, ALS, and can be used to evaluate the degree of AP-related nerve damage and treatment response | ||||