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1135

Parameter
Biomarker APOE ε4 Full name Apolipoprotein E ε4 allele Molecular Type Nucleic acid (DNA)
Molecular Formula Molecular Weight Core Functional Dimensions Susceptibility
Disease Acute pancreatitis (AP) Disease Subtypes /
Organ Pancreas Test Sample / Technology Platform Whole blood (genotyping)
Pathobiological Mechanisms Influence of lipid metabolism, reduce A beta removal efficiency, carriers AP related neurological complications increased risk and the time in advance
Clinical Availability Status Clinical available (risk assessment) : conventional genetic tests available, but only for risk assessment, not for diagnosis, involves ethical issues
Notes and Dynamics It is the core variable in establishing the risk stratification model of neurological complications of AP. Important stratification factor is related to treatment trials

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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