Parameter
| Biomarker | tRF-36 | Full name | tRNA-derived fragment 36 | Molecular Type | Trna-derived small RNA (tsRNA) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis and Prognosis | ||
| Disease | Acute pancreatitis (AP) | Disease Subtypes | / | ||
| Organ | Pancreas | Test Sample / Technology Platform | Serum (RNA sequencing, RNA pull - down) | ||
| Pathobiological Mechanisms | Interact with IGF2BP3, targeting the p53 mRNA m6A modification site, enhance its stability, and promote pancreatic acinar cell ferroptosis, aggravating the AP | ||||
| Clinical Availability Status | Cutting-edge research: clinical serum samples to rise significantly, expressed in cells in the model on inflammatory factor levels after low | ||||
| Notes and Dynamics | High stability, strong specificity, is expected to become a noninvasive biomarkers in early diagnosis of AP, its related pathways can be used as therapeutic targets | ||||